Description

Thiophen-2-Ylmethyl-Phosphonic Acid Diethyl Ester is a high-purity organophosphorus compound, specifically a phosphonic acid ester derivative of thiophene. This chemical serves as a versatile and critical building block (synthon) in advanced organic synthesis, enabling the introduction of a functionalized thiophene moiety. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the thiophene scaffold imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphine-based ligands used in transition metal catalysis for fine chemical manufacturing.
• Material Science Research: Employed in the development of organic semiconductors, conductive polymers, and other electronic materials due to the electron-rich thiophene unit.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Thiophen-2-Ylmethyl-Phosphonic Acid Diethyl Ester
CAS No.	2026-42-8
Molecular Formula	C10H15O3PS
Molecular Weight	246.26 g/mol
Synonyms	Diethyl (2-Thienylmethyl)phosphonate; (Thiophen-2-ylmethyl)phosphonic Acid Diethyl Ester; Diethyl (Thiophen-2-ylmethyl)phosphonate; 2-Thienylmethylphosphonic Acid Diethyl Ester; Diethyl 2-Thienylmethylphosphonate; Phosphonic Acid, P-[(2-Thienyl)methyl]-, Diethyl Ester; Diethyl (2-Thienylmethyl)phosphonate
EINECS	217-967-5

Quality Control

Our Thiophen-2-Ylmethyl-Phosphonic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.