Description

2-Methoxy-4-Nitrophenyl Isocyanide is a specialized aromatic isocyanide building block of significant interest in synthetic organic chemistry. Its unique structure, featuring both an electron-donating methoxy group and an electron-withdrawing nitro group, makes it a valuable precursor for constructing complex heterocycles and functional materials. This compound is primarily sought after by research institutions and chemical manufacturers engaged in the development of pharmaceuticals, agrochemicals, and advanced organic materials. We supply this high-purity intermediate with a commitment to consistent quality and reliable global logistics.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly for constructing heterocyclic cores.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its reactivity to create bioactive molecules.
• Material Science: Employed as a monomer or precursor in the synthesis of functional polymers, coordination polymers, and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Development: Utilized in click chemistry and bioorthogonal reactions for labeling and studying biological systems.
• Catalyst Ligand Synthesis: Acts as a precursor for isocyanide-derived ligands used in transition metal catalysis.
• Academic & Industrial R&D: A fundamental reagent for methodological development in organic synthesis and novel reaction discovery.

Basic Information

Product Name	2-Methoxy-4-Nitrophenyl Isocyanide
CAS No.	2008-62-0
Molecular Formula	C8H6N2O3
Molecular Weight	178.15 g/mol
Synonyms	4-Nitro-2-methoxyphenyl isocyanide; 1-Isocyano-2-methoxy-4-nitrobenzene; 2-Methoxy-4-nitrobenzenisocyanide; 2-Methoxy-4-nitro-phenylisocyanid; (2-Methoxy-4-nitrophenyl)isocyanide; 4-Nitro-o-anisyl isocyanide; 2-Methoxy-4-nitrobenzonitrile, N-oxide (related); Isocyanic acid, (2-methoxy-4-nitrophenyl) ester
EINECS	Contact for details

Quality Control

Our 2-Methoxy-4-Nitrophenyl Isocyanide is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications. We adhere to relevant industry standards to support our clients' research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. The compound is moisture-sensitive and should be handled under an inert atmosphere when appropriate.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.