Description

(17α)-Pregn-4-Ene-3,20-Dione is a high-purity steroid intermediate, also known as 17α-Hydroxyprogesterone, with the CAS registry number 2000-66-0. This compound is a critical building block in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is essential for manufacturers in the pharmaceutical and life sciences sectors requiring reliable, high-quality raw materials for research, development, and production. Our supply ensures consistent quality and purity to meet stringent industry demands.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of corticosteroids, progestogens, and other therapeutic steroid hormones.
• API Synthesis: Used in the multi-step manufacturing process of various steroid-based Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Serves as a standard or starting material in metabolic pathway studies and steroidogenesis research.
• Reference Standard: Utilized as a certified reference material (CRM) in analytical laboratories for method development and quality control.
• Veterinary Pharmaceuticals: Employed in the development and production of steroid treatments for animal health.

Basic Information

Product Name	(17α)-Pregn-4-Ene-3,20-Dione
CAS No.	2000-66-0
Molecular Formula	C21H30O3
Molecular Weight	330.46 g/mol
Synonyms	17α-Hydroxyprogesterone; 17α-OHP; 17α-Hydroxy-4-pregnene-3,20-dione; 17α-Hydroxypregn-4-ene-3,20-dione; 17α-Progesterone; 17α-HP; 17-Hydroxyprogesterone (α-isomer); Pregn-4-ene-3,20-dione, 17α-hydroxy-
EINECS	217-900-9

Quality Control

Our (17α)-Pregn-4-Ene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, to ensure it meets the high standards required for pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and the absence of critical impurities. We support compliance with cGMP and relevant pharmacopoeial guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in the original packaging away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.