Description

Thiothiamine is a sulfur-containing derivative of vitamin B1 (thiamine) with significant biochemical activity. This compound is valued for its role as a key intermediate and research chemical in the development of novel pharmaceutical and nutraceutical agents. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, life sciences, and advanced chemical synthesis sectors.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of advanced thiamine analogs and prodrugs for therapeutic applications.
• Biochemical Research: Used in metabolic studies to investigate sulfur metabolism and the biochemical pathways of thiamine and its derivatives.
• Nutraceutical Development: Employed in R&D for formulating specialized dietary supplements and exploring enhanced bioavailability forms of vitamin B1.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Chemical Synthesis: Utilized as a specialized reagent in organic synthesis for introducing sulfur-containing heterocyclic structures.

Basic Information

Product Name	Thiothiamine
CAS No.	299-35-4
Molecular Formula	C12H16N4OS2
Molecular Weight	296.41 g/mol
Synonyms	Thiamine Monosulfide; Thiamine Sulfide; Vitamin B1 Sulfide; Thio-Thiamine; 3-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium Chloride, Sulfide; Thiamine Monosulfide Hydrochloride (related salt); TTD (Thiamine Thiazolone Disulfide analog)
EINECS	Contact for details

Quality Control

Our Thiothiamine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.