Description

[1,3]Thiazolo[5,4-B]Pyridine CAS NO 273-84-7 is a high-value fused heterocyclic compound featuring a thiazole ring annulated to a pyridine core. This unique bicyclic structure makes it a critical advanced pharmaceutical intermediate and a versatile organic synthesis building block. It is primarily sought after by research institutions and chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic scaffold.
• Organic Light-Emitting Diodes (OLEDs): Acts as an electron-transporting or host material in the fabrication of efficient OLED devices.
• Ligand Synthesis: Utilized for creating novel nitrogen-sulfur containing ligands for catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Chemistry: Functions as a core structure for synthesizing specialized dyes and optical brighteners.
• Academic & R&D: A valuable compound for methodological studies in heterocyclic chemistry and for exploring new chemical spaces.

Basic Information

Product Name	[1,3]Thiazolo[5,4-B]Pyridine
CAS No.	273-84-7
Molecular Formula	C6H4N2S
Molecular Weight	136.17 g/mol
Synonyms	Thiazolo[5,4-b]pyridine; 1,3-Thiazolo[5,4-b]pyridine; [1,3]Thiazolo[5,4-b]pyridine; Thiazolo(5,4-b)pyridine; NSC 221981; 273-84-7; 5,4-b-Thiazolopyridine
EINECS	205-992-9

Quality Control

Our production of [1,3]Thiazolo[5,4-B]Pyridine adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support custom synthesis and can tailor specifications to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage under an inert atmosphere is recommended.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.