Description

2-Chloroethyl Chloroformate is a versatile and highly reactive organic intermediate, primarily used as a chloroformylating and protecting group reagent. Its value lies in its ability to efficiently introduce the chloroethyl chloroformate moiety, enabling the synthesis of complex molecules in a controlled manner. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the production of active pharmaceutical ingredients (APIs), crop protection agents, and advanced polymers.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of various active pharmaceutical ingredients (APIs), including potential anticancer and antiviral agents.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, insecticides, and fungicides, where it acts as a crucial reagent for introducing specific functional groups.
• Polymer Chemistry: Serves as a monomer or modifying agent in the production of specialty polymers, such as polycarbonates and polyurethanes, with tailored properties.
• Peptide Synthesis: Functions as a protecting group reagent for amino acids during solid-phase and solution-phase peptide synthesis.
• Chemical Research & Development: A valuable tool in organic synthesis laboratories for constructing complex molecular architectures and exploring new chemical reactions.
• Dye and Pigment Manufacturing: Employed in the synthesis of certain advanced colorants and photographic chemicals.

Basic Information

Product Name	2-Chloroethyl Chloroformate
CAS No.	27-11-2
Molecular Formula	C3H4Cl2O2
Molecular Weight	142.97 g/mol
Synonyms	Chloroethyl Chloroformate; 2-Chloroethyl Carbonochloridate; Ethanol, 2-chloro-, chloroformate; Chloroformic Acid 2-Chloroethyl Ester; β-Chloroethyl Chloroformate; NSC 8806; UN 2827
EINECS	200-386-5

Quality Control

Our 2-Chloroethyl Chloroformate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for demanding applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at temperatures between 2°C and 8°C. Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	1.38 - 1.42 g/mL
Refractive Index (n20D)	1.435 - 1.445

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.