Description

Ethyl n-(tert-Butoxycarbonyl)-n-((1-(Hydroxymethyl)Cyclopropyl)Methyl)Glycinate is a sophisticated, high-purity chemical building block designed for advanced synthetic chemistry. This compound is valued for its role as a protected amino acid derivative, offering precise control in the construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and peptide-based therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce modified glycine residues with orthogonal protecting groups.
• Protease Inhibitor Development: Serves as a precursor in the creation of novel enzyme inhibitors due to its unique cyclopropylmethyl and hydroxymethyl motifs.
• Chemical Biology Research: Employed in the design and synthesis of activity-based probes and molecular tools for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.
• Agrochemical Research: Investigated as an intermediate for novel plant protection agents with specific modes of action.

Basic Information

Product Name	Ethyl n-(tert-Butoxycarbonyl)-n-((1-(Hydroxymethyl)Cyclopropyl)Methyl)Glycinate
CAS No.	1998216-45-7
Molecular Formula	C15H27NO5
Molecular Weight	301.38 g/mol
Synonyms	Ethyl N-Boc-N-((1-(hydroxymethyl)cyclopropyl)methyl)glycinate; Boc-N-((1-(Hydroxymethyl)cyclopropyl)methyl)glycine ethyl ester; N-(tert-Butoxycarbonyl)-N-[(1-(hydroxymethyl)cyclopropyl)methyl]glycine Ethyl Ester; Glycine, N-[(1-(hydroxymethyl)cyclopropyl)methyl]-N-[(1,1-dimethylethoxy)carbonyl]-, ethyl ester; Boc-Cpgm-Gly-OEt; 1998216-45-7; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our Ethyl n-(tert-Butoxycarbonyl)-n-((1-(Hydroxymethyl)Cyclopropyl)Methyl)Glycinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.