Description

1-(5-Bromopyridin-3-Yl)Cyclopropanamine Hcl is a high-purity, advanced pharmaceutical intermediate featuring a brominated pyridine core fused with a cyclopropanamine moiety. This compound is valued for its role as a critical building block in the synthesis of novel, small-molecule active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is essential for research and development chemists and process scale-up teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new drug candidates and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, leveraging its halogenated heterocyclic structure.
• Ligand & Catalyst Development: Serves as a sophisticated ligand precursor in organometallic chemistry and catalysis for asymmetric synthesis.
• Chemical Biology Probe Synthesis: Employed to create molecular probes for studying enzyme function and protein-ligand interactions in R&D.
• Material Science: A building block for creating functionalized polymers or organic electronic materials with specific optoelectronic properties.

Basic Information

Product Name	1-(5-Bromopyridin-3-Yl)Cyclopropanamine Hcl
CAS No.	1993189-05-1
Molecular Formula	C8H10BrClN2
Molecular Weight	249.53 g/mol
Synonyms	1-(5-Bromo-3-pyridinyl)cyclopropanamine hydrochloride; 1-(5-Bromopyridin-3-yl)cyclopropan-1-amine hydrochloride; 3-(1-Aminocyclopropyl)-5-bromopyridine hydrochloride; Cyclopropanamine, 1-(5-bromo-3-pyridinyl)-, hydrochloride; 5-Bromo-3-(1-aminocyclopropyl)pyridine HCl
EINECS	Contact for details

Quality Control

Our 1-(5-Bromopyridin-3-Yl)Cyclopropanamine Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.