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Azido-Peg9-Alcohol CAS NO 1984776-37-5


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CAS No.:1984776-37-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Azido-Peg9-Alcohol is a heterobifunctional polyethylene glycol (PEG) derivative featuring a reactive azide group at one terminus and a hydroxyl group at the other. This unique structure makes it an invaluable building block for creating custom linkers and spacers in bioconjugation and materials science. It is primarily used by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing targeted drug delivery systems, diagnostic agents, and functionalized surfaces.

Application

  • Bioconjugation Linker: Used to covalently attach biomolecules (e.g., antibodies, peptides, oligonucleotides) to other entities like drugs, dyes, or solid surfaces via click chemistry.
  • ADC (Antibody-Drug Conjugate) Development: Serves as a hydrophilic, flexible spacer to connect cytotoxic payloads to monoclonal antibodies, improving solubility and pharmacokinetics.
  • PEGylation Reagent: The hydroxyl group can be further functionalized to introduce PEG chains onto proteins or nanoparticles, enhancing stability and reducing immunogenicity.
  • Polymer and Materials Modification: Enables the introduction of azide functionality into polymers, hydrogels, or surfaces for subsequent click chemistry modifications.
  • Diagnostic Probe Synthesis: Facilitates the construction of imaging probes and biosensors by linking targeting molecules to reporter groups.
  • Cross-linking Agent: Used in the synthesis of cross-linked networks or dendrimers for specialized material properties.

Basic Information

Product Name Azido-Peg9-Alcohol
CAS No. 1984776-37-5
Molecular Formula C19H39N3O10
Molecular Weight 469.53 g/mol
Synonyms Azido-PEG9-OH; 1-Azido-3,6,9,12,15,18,21,24,27-nonaoxanonacosan-29-ol; 2-[2-[2-[2-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol; Azido-EG9-OH; N3-PEG9-OH; PEG9-Azide Alcohol; Azido-Polyethylene Glycol9-Alcohol; 29-Azido-3,6,9,12,15,18,21,24,27-nonaoxanonacosan-1-ol
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Quality Control

Our Azido-Peg9-Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item Specification
Appearance Colorless to pale yellow viscous liquid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%
Molecular Weight Confirmation (MS) Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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