Description

Azido-Peg3-Phosphonic Acid is a heterobifunctional PEG linker featuring an azide group and a phosphonic acid moiety, connected by a triethylene glycol spacer. This compound is a critical building block in bioconjugation and materials science, enabling the stable attachment of biomolecules to surfaces via robust phosphonate-metal interactions. It is primarily utilized by researchers and manufacturers in the pharmaceutical, diagnostics, and nanotechnology sectors for applications such as surface functionalization, drug delivery system development, and the creation of bio-compatible coatings.

Application

• Surface Functionalization: Used to create self-assembled monolayers (SAMs) on metal oxide surfaces (e.g., titanium, stainless steel) for biosensor and implant coating applications.
• Bioconjugation & Click Chemistry: The azide group enables copper-catalyzed or strain-promoted azide-alkyne cycloaddition (CuAAC/SPAAC) for labeling proteins, peptides, or oligonucleotides with a phosphonate anchor.
• Drug Delivery Systems: Serves as a linker to tether therapeutic agents or targeting ligands to nanoparticle cores or inorganic carriers for controlled release.
• Material Science: Incorporation into polymers or hydrogels to introduce phosphonate groups for enhanced metal chelation, adhesion, or mineralization properties.
• Diagnostic Assays: Immobilization of capture antibodies or DNA probes on phosphonate-coated microplates or chips for ELISA and microarray platforms.
• Dental & Orthopedic Materials: Modification of implant surfaces to improve osseointegration and biocompatibility through phosphonate-based bonding.

Basic Information

Product Name	Azido-Peg3-Phosphonic Acid
CAS No.	1964503-38-5
Molecular Formula	C9H20N3O7P
Molecular Weight	313.25 g/mol
Synonyms	3-Azidopropyl-PEG3-phosphonic acid; 11-Azido-3,6,9-trioxaundecan-1-phosphonic acid; Azido-PEG3-phosphonate; N3-PEG3-phosphonic acid; Azido-tri(ethylene glycol)-phosphonic acid; Phosphonic acid, P-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]-; Azido-PEG3-C1-phosphonic acid; PEG3-Azide-Phosphonic Acid
EINECS	Contact for details

Quality Control

Our Azido-Peg3-Phosphonic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (NMR)	Conforms to structure
Identification (IR)	Presence of characteristic azide and phosphonate bands
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.