Description

(R)-1-(6-Chloropyridin-2-Yl)Ethanamine Hydrochloride is a high-purity chiral amine building block of significant importance in modern pharmaceutical research and development. Its core value lies in its role as a key intermediate for synthesizing active pharmaceutical ingredients (APIs) and other biologically active compounds, particularly those targeting the central nervous system. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, especially in neurological and psychiatric therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced, enantiomerically pure pesticides and herbicides.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis to create other high-value enantiopure compounds.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and structure-activity relationships (SAR).
• Process Chemistry: Utilized in the scale-up and optimization of manufacturing routes for complex organic molecules requiring the (R)-enantiomer configuration.

Basic Information

Product Name	(R)-1-(6-Chloropyridin-2-Yl)Ethanamine Hydrochloride
CAS No.	1956436-85-3
Molecular Formula	C7H10Cl2N2
Molecular Weight	193.07 g/mol
Synonyms	(R)-1-(6-Chloro-2-pyridinyl)ethanamine hydrochloride; (R)-α-Methyl-6-chloro-2-pyridinemethanamine hydrochloride; (R)-6-Chloro-2-(1-aminoethyl)pyridine hydrochloride; (R)-2-(1-Aminoethyl)-6-chloropyridine hydrochloride; (R)-1-(6-Chloro-pyridin-2-yl)-ethylamine hydrochloride; (R)-6-Chloro-2-(aminomethyl)pyridine hydrochloride (isomer specific); (R)-Enantiomer of 1-(6-Chloropyridin-2-yl)ethanamine HCl
EINECS	Contact for details

Quality Control

Our (R)-1-(6-Chloropyridin-2-Yl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, meeting the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral purity, and impurity profiles is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.