Description

2-(((tert-Butyldimethylsilyl)Oxy)Methyl)-7-Iodofuro[3,2-C]Pyridine (Wxc04429) is a high-value, organosilicon-protected heterocyclic building block, specifically designed for advanced synthetic chemistry. This compound matters because it provides a strategically functionalized scaffold, combining a halogen handle for cross-coupling reactions with a silyl-protected alcohol for selective deprotection and further derivatization. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic compounds for drug discovery and development programs.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings to introduce diverse aryl and alkyl groups.
• Medicinal Chemistry: Used to build and explore structure-activity relationships (SAR) in libraries targeting various biological pathways.
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients with enhanced efficacy and selectivity.
• Material Science Research: Potential monomer or precursor for creating novel organic electronic materials or ligands for catalysis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring precise functional group manipulation.

Basic Information

Product Name	2-(((tert-Butyldimethylsilyl)Oxy)Methyl)-7-Iodofuro[3,2-C]Pyridine (Wxc04429)
CAS No.	1956364-46-7
Molecular Formula	C15H22INO2Si
Molecular Weight	403.34 g/mol
Synonyms	7-Iodo-2-(((tert-butyldimethylsilyl)oxy)methyl)furo[3,2-c]pyridine; 2-(((tert-Butyldimethylsilyl)oxy)methyl)-7-iodofuro[3,2-c]pyridine; WXC-04429; WXC04429; TBDMS-protected 7-iodofuro[3,2-c]pyridine methanol; 7-Iodo-2-((tert-butyldimethylsilyloxy)methyl)furo[3,2-c]pyridine; (7-Iodofuro[3,2-c]pyridin-2-yl)methoxy-tert-butyldimethylsilane
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 2-(((tert-Butyldimethylsilyl)Oxy)Methyl)-7-Iodofuro[3,2-C]Pyridine (Wxc04429) is characterized and verified using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate to maximize long-term stability. Keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.