Description

Ethyl 2,2-Difluoro-3-(Methylamino)Propanoate Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique difluoro and methylamino functional groups. This compound is essential for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of targeted therapeutics. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated drug candidates, including protease inhibitors and kinase inhibitors.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides with enhanced activity and selectivity.
• Chemical Synthesis: Serves as a versatile precursor for introducing the 2,2-difluoro-3-(methylamino)propanoate moiety into more complex molecules.
• Life Science Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) in medicinal chemistry.
• Process Chemistry: Used for route scouting and optimization in the commercial-scale manufacturing of fluorinated compounds.

Basic Information

Product Name	Ethyl 2,2-Difluoro-3-(Methylamino)Propanoate Hydrochloride
CAS No.	1956311-12-8
Molecular Formula	C6H12ClF2NO2
Molecular Weight	203.62 g/mol
Synonyms	Ethyl 2,2-Difluoro-3-(Methylamino)Propionate Hydrochloride; 2,2-Difluoro-3-(methylamino)propanoic Acid Ethyl Ester Hydrochloride; 3-(Methylamino)-2,2-difluoropropanoic Acid Ethyl Ester Hydrochloride; Ethyl 3-(Methylamino)-2,2-difluoropropanoate HCl; Methylamino Difluoropropanoate Ethyl Ester Hydrochloride; CAS 1956311-12-8
EINECS	Contact for details

Quality Control

Our Ethyl 2,2-Difluoro-3-(Methylamino)Propanoate Hydrochloride is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.