Description

tert-Butyl 2-Oxo-[1,3]Oxazolo[4,5-B]Pyridine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries engaged in developing new drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing fused oxazolopyridine cores, enabling structure-activity relationship (SAR) studies and lead optimization.
• Research & Development (R&D): Serves as a valuable reagent in academic and industrial research laboratories for exploring new chemical entities and reaction methodologies.
• Process Chemistry: Employed in scaling up synthetic routes from milligram to kilogram scale during the drug development and pre-clinical phases.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client-specific projects.

Basic Information

Product Name	tert-Butyl 2-Oxo-[1,3]Oxazolo[4,5-B]Pyridine-3-Carboxylate
CAS No.	1951445-08-1
Molecular Formula	C11H12N2O4
Molecular Weight	236.23 g/mol
Synonyms	3-(tert-Butoxycarbonyl)-2-oxo-[1,3]oxazolo[4,5-b]pyridine; tert-Butyl 2-oxooxazolo[4,5-b]pyridine-3-carboxylate; 2-Oxo-[1,3]oxazolo[4,5-b]pyridine-3-carboxylic acid tert-butyl ester; Oxazolo[4,5-b]pyridine-3-carboxylic acid, 2-oxo-, 1,1-dimethylethyl ester; 1951445-08-1; tert-Butyl 2-oxo-1,3-oxazolo[4,5-b]pyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced intermediates. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for each lot are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.