Description

Methyl 4-Methanesulfonyl-2-(Trifluoromethyl)Benzoate CAS NO 1951440-91-7 is a high-purity, advanced pharmaceutical intermediate characterized by its distinct sulfonyl and trifluoromethyl functional groups. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring enhanced metabolic stability and bioavailability. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule drugs, agrochemicals, and specialty organic materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the trifluoromethyl group contributes to biological activity and environmental persistence.
• Material Science: Serves as a precursor for specialty polymers and liquid crystals, leveraging its aromatic and electron-withdrawing substituents.
• Organic Synthesis: A versatile reagent for introducing the 4-methanesulfonyl-2-(trifluoromethyl)benzoyl moiety into more complex molecular architectures via ester hydrolysis or cross-coupling reactions.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	Methyl 4-Methanesulfonyl-2-(Trifluoromethyl)Benzoate
CAS No.	1951440-91-7
Molecular Formula	C10H9F3O4S
Molecular Weight	282.24 g/mol
Synonyms	Methyl 4-(Methylsulfonyl)-2-(trifluoromethyl)benzoate; Benzoic acid, 4-(methylsulfonyl)-2-(trifluoromethyl)-, methyl ester; 4-Methanesulfonyl-2-trifluoromethylbenzoic acid methyl ester; Methyl 4-(methylsulphonyl)-2-(trifluoromethyl)benzoate; Methyl 2-Trifluoromethyl-4-methylsulfonylbenzoate; 1951440-91-7; Methyl 4-Methanesulfonyl-2-(Trifluoromethyl)Benzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Methanesulfonyl-2-(Trifluoromethyl)Benzoate adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.