Description

4,7-Diaza-Spiro[2.5]Octane-4-Carboxylic Acid Benzyl Ester (Hydrochloride) is a high-value, spirocyclic building block and intermediate in advanced organic synthesis. This compound matters for its unique constrained spirocyclic structure, which is crucial for modulating the physicochemical and biological properties of target molecules in drug discovery. It is primarily needed by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Protease Inhibitor Scaffold: Used in the research and development of protease inhibitors, leveraging its diaza-spiro structure to create potent and selective enzyme binders.
• Agrochemical Synthesis: Serves as a sophisticated intermediate in the creation of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Peptidomimetics & Constrained Peptide Analogues: The spirocyclic core is utilized to introduce conformational rigidity into peptide chains, enhancing stability and bioavailability.
• Ligand Synthesis for Catalysis: Acts as a precursor for chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.

Basic Information

Product Name	4,7-Diaza-Spiro[2.5]Octane-4-Carboxylic Acid Benzyl Ester (Hydrochloride)
CAS No.	1951440-78-0
Molecular Formula	C15H19ClN2O2
Molecular Weight	294.78 g/mol
Synonyms	Benzyl 4,7-diaza-spiro[2.5]octane-4-carboxylate hydrochloride; 4,7-Diaza-spiro[2.5]octane-4-carboxylic acid benzyl ester HCl; 1,4-Diazaspiro[2.5]octane-4-carboxylic acid phenylmethyl ester hydrochloride; 4-Carboxy-4-benzyloxycarbonyl-1,4-diazaspiro[2.5]octane hydrochloride; Spirocyclic diazaoctane benzyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific batch results are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.