Description

Acetic Acid, 2-[3-(2-Aminoethoxy)Propoxy]-, 1,1-Dimethylethyl Ester is a specialized organic compound featuring a protected carboxylic acid group and a polyether-linked primary amine. This unique bifunctional structure makes it a valuable building block for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector who require high-purity, functionalized intermediates for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring polyether-amine linkers or protected carboxyl functionalities.
• Bioconjugation Reagent: Used in the development of antibody-drug conjugates (ADCs) and other biopharmaceuticals where controlled linkage between biomolecules and payloads is critical.
• Polymer Chemistry: Serves as a monomer or chain extender for creating specialized polyesters, polyamides, or polyurethanes with tailored hydrophilic and reactive properties.
• Agrochemical Synthesis: Employed in the research and production of advanced herbicides, fungicides, or plant growth regulators that benefit from its specific molecular architecture.
• Ligand and Catalyst Development: Useful for constructing complex chelating ligands used in catalysis or metal ion sequestration.
• Surface Modification Agent: Can be applied to modify material surfaces, introducing amine groups for further functionalization under mild conditions.

Basic Information

Product Name	Acetic Acid, 2-[3-(2-Aminoethoxy)Propoxy]-, 1,1-Dimethylethyl Ester
CAS No.	1948273-09-3
Molecular Formula	C13H27NO5
Molecular Weight	277.36 g/mol
Synonyms	tert-Butyl 2-[3-(2-aminoethoxy)propoxy]acetate; 2-[3-(2-Aminoethoxy)propoxy]acetic acid tert-butyl ester; tert-Butyl (2-(2-(3-aminopropoxy)ethoxy)acetate); Boc-AEEA-OH tert-Butyl ester (common abbreviation); AEEA linker tert-butyl ester; 2,2-Dimethylpropyl 2-[3-(2-aminoethoxy)propoxy]acetate; Polyethylene glycol derivative, amino-PEG2-acetic acid t-butyl ester; N/A (Contact for details)
EINECS	Not yet assigned / Contact for details

Quality Control

Our Acetic Acid, 2-[3-(2-Aminoethoxy)Propoxy]-, 1,1-Dimethylethyl Ester is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We can support development projects requiring compliance with cGMP and other relevant regulatory guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.