Description

(2S,3S)-2-Amino-3-Methyl-Pentanoic Acidmethyl Ester CAS NO 1943758-28-8 is a high-purity, non-proteinogenic amino acid derivative with a defined stereochemistry. This compound is a critical chiral building block for the synthesis of complex pharmaceuticals and bioactive peptides, offering precise control over the three-dimensional structure of the final molecule. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, including enzyme inhibitors and peptide-based drugs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to introduce specific, sterically defined amino acid residues.
• Biochemical Research: Serves as a standard or reagent in enzymatic studies and metabolic pathway research.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in stereoselective organic synthesis.
• Proteomics & Diagnostics: Potential use in the development of specialized reagents and probes for biological assays.

Basic Information

Product Name	(2S,3S)-2-Amino-3-Methyl-Pentanoic Acidmethyl Ester
CAS No.	1943758-28-8
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	L-2-Amino-3-methylpentanoic acid methyl ester; (2S,3S)-2-Amino-3-methylvaleric acid methyl ester; Methyl (2S,3S)-2-amino-3-methylpentanoate; (2S,3S)-3-Methylnorvaline methyl ester; (S,S)-2-Amino-3-methylpentanoic acid methyl ester; Methyl L-2-amino-3-methylpentanoate; (2S,3S)-Amino acid ester derivative
EINECS	Contact for details

Quality Control

Our (2S,3S)-2-Amino-3-Methyl-Pentanoic Acidmethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.