Description

n-Boc-12-Azidododecan-1-Amine CAS NO 1943755-95-0 is a specialized bifunctional chemical building block featuring both a protected amine (Boc) and a terminal azide group. This compound is essential for advanced organic synthesis, particularly in click chemistry and bioconjugation applications where precise, high-yield coupling is required. It is primarily utilized by researchers and manufacturers in pharmaceutical development, materials science, and proteomics for creating novel drug conjugates, polymers, and labeled biomolecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Click Chemistry Reagent: Utilized in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for efficient and selective ligation.
• Bioconjugation: For site-specific labeling of proteins, peptides, and other biomolecules with fluorescent dyes, polymers, or solid surfaces.
• Polymer & Materials Science: Serves as a functional monomer or cross-linker in the development of smart polymers, hydrogels, and surface-modified nanomaterials.
• Proteomics Research: Used in activity-based protein profiling (ABPP) and other chemical proteomics strategies to study enzyme function.
• Chemical Biology Tool: Enables the synthesis of chemical probes for studying biological pathways and cellular processes.

Basic Information

Product Name	n-Boc-12-Azidododecan-1-Amine
CAS No.	1943755-95-0
Molecular Formula	C₁₇H₃₄N₄O₂
Molecular Weight	326.48 g/mol
Synonyms	12-Azido-1-[(tert-butoxycarbonyl)amino]dodecane; 1-Amino-12-azidododecane N-Boc derivative; tert-Butyl (12-azidododecyl)carbamate; N-(tert-Butoxycarbonyl)-12-azidododecylamine; Boc-12-azidododecylamine; Boc-NH-(CH₂)₁₁-N₃; Azido-PEG₁₁-Boc-amine; 12-Azidododecan-1-amine, N-Boc-protected
EINECS	Contact for details

Quality Control

Our n-Boc-12-Azidododecan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Keep away from heat, sparks, open flames, and incompatible materials. Due to its light-sensitive and easily oxidized nature, prolonged exposure to light and air should be avoided.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical: 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.