Description

Cyclohexanecarboxylic Acid, 4-(Hydroxymethyl)-, 1,1-Dimethyl Ester, trans- is a high-purity, synthetically valuable chiral intermediate. This compound is specifically engineered for advanced pharmaceutical and fine chemical synthesis, offering a defined stereochemistry critical for producing active molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Chiral Auxiliary/Synthon: Utilized in asymmetric synthesis to introduce the trans-cyclohexane scaffold with a hydroxymethyl handle for further functionalization.
• Agrochemical Research: Intermediate in the development of new generation herbicides and fungicides with specific stereochemical requirements.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in homogeneous catalysis.
• Material Science Monomer: Potential monomer for synthesizing specialty polymers with unique thermal and mechanical properties.
• Academic & Industrial R&D: Used in exploratory chemistry for method development and the creation of compound libraries for screening.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 4-(Hydroxymethyl)-, 1,1-Dimethyl Ester, trans-
CAS No.	1943744-53-3
Molecular Formula	C10H18O4
Molecular Weight	202.25 g/mol
Synonyms	trans-4-(Hydroxymethyl)cyclohexanecarboxylic Acid 1,1-Dimethyl Ester; (1r,4r)-4-(Hydroxymethyl)cyclohexane-1-carboxylic Acid Dimethyl Ester; Dimethyl trans-4-(Hydroxymethyl)cyclohexane-1-carboxylate; trans-Dimethyl 4-(Hydroxymethyl)cyclohexanecarboxylate; 4-Hydroxymethyl-cyclohexanecarboxylic Acid Dimethyl Ester, trans-; (trans)-4-Carbomethoxycyclohexylmethanol Methyl Ester; (1R,4R)-4-(Hydroxymethyl)cyclohexyl Methyl Carbonate Derivative
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 4-(Hydroxymethyl)-, 1,1-Dimethyl Ester, trans- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% trans-isomer
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.