Description

2,8-Diazaspiro[4.5]Decan-8-Yl(Thiophen-3-Yl)Methanone is a high-value, spirocyclic organic building block featuring a diazaspirodecane core fused with a thiophene carbonyl moiety. This compound matters as a sophisticated chemical intermediate, offering unique three-dimensional structural complexity critical for modulating the physicochemical properties of advanced molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, particularly in the synthesis of novel active ingredients targeting the central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, especially for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to improve potency, selectivity, and metabolic stability.
• Agrochemical Development: Serves as a precursor in the creation of new active ingredients for crop protection products.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic Research: Employed in university and institutional labs for methodological development in heterocyclic and spirocyclic chemistry.

Basic Information

Product Name	2,8-Diazaspiro[4.5]Decan-8-Yl(Thiophen-3-Yl)Methanone
CAS No.	1940113-95-0
Molecular Formula	C13H16N2OS
Molecular Weight	248.35 g/mol
Synonyms	8-(Thiophene-3-carbonyl)-2,8-diazaspiro[4.5]decane; (Thiophen-3-yl)(2,8-diazaspiro[4.5]decan-8-yl)methanone; 3-[(2,8-Diazaspiro[4.5]decan-8-yl)carbonyl]thiophene; 2,8-Diazaspiro[4.5]decane-8-carbothiophen-3-yl ketone; 1940113-95-0; Thiophene-3-carboxylic acid 2,8-diazaspiro[4.5]decan-8-yl ester (tautomeric form).
EINECS	Contact for details

Quality Control

Our 2,8-Diazaspiro[4.5]Decan-8-Yl(Thiophen-3-Yl)Methanone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency, meeting the stringent requirements of pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.