Description

tert-Butyl 3-(2-(2-Iodoethoxy)Ethoxy)Propanoate is a specialized organic building block featuring a protected carboxylic acid group and a polyethylene glycol-like spacer terminated with an iodoalkyl moiety. This unique bifunctional structure makes it a valuable intermediate for the synthesis of complex molecules, particularly in pharmaceutical research and advanced material science. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing targeted drug delivery systems, bioconjugates, and functionalized polymers.

Application

• Pharmaceutical Intermediate: Key synthon for the development of antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Bioconjugation Linker: Used to attach drugs, dyes, or other functional groups to proteins, peptides, or nanoparticles via its reactive iodo group.
• Polymer Functionalization: Serves as a monomer or modifier for creating functional polymers with tailored properties for biomedical applications.
• Prodrug Synthesis: Employed in constructing prodrugs where the tert-butyl ester can be cleaved to release the active carboxylic acid moiety.
• Material Science Research: Used to synthesize surface-modified materials and cross-linked hydrogels for controlled release systems.
• Chemical Biology Probes: Facilitates the creation of molecular probes for studying biological processes and interactions.

Basic Information

Item	Details
Product Name	tert-Butyl 3-(2-(2-Iodoethoxy)Ethoxy)Propanoate
CAS No.	1938057-43-2
Molecular Formula	C11H21IO4
Molecular Weight	344.19 g/mol
Synonyms	1,2-Bis(2-iodoethoxy)ethane tert-butyl ester; 3-[2-(2-Iodoethoxy)ethoxy]propanoic acid tert-butyl ester; tert-Butyl 3-[2-(2-iodoethoxy)ethoxy]propionate; PEG2-Iodide tert-butyl ester; 2-[2-(2-Iodoethoxy)ethoxy]ethyl propionate tert-butyl derivative; Iodo-PEG2-t-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(2-(2-Iodoethoxy)Ethoxy)Propanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your research and development and regulatory filing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling should be performed under subdued light or using amber glassware when possible.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (HPLC, NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.