Description

Ethyl 5-Chloro-2-Fluoro-4-Hydroxybenzoate is a high-purity, synthetically valuable benzoate ester derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring chloro, fluoro, and hydroxy substituents, makes it an essential intermediate for the development of complex active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily targeted at R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates for their synthesis pipelines.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in fluorinated pharmaceutical compounds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides where the chloro-fluoro-hydroxy substitution pattern is required for bioactivity.
• Liquid Crystal & OLED Material Research: Serves as a precursor for fluorinated aromatic compounds used in electronic materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, esterifications, and other transformations to create more complex molecular architectures.
• Chemical Research & Development: Utilized in academic and industrial labs for method development and exploring new chemical entities.

Basic Information

Product Name	Ethyl 5-Chloro-2-Fluoro-4-Hydroxybenzoate
CAS No.	1936365-38-6
Molecular Formula	C9H8ClFO3
Molecular Weight	218.61 g/mol
Synonyms	Ethyl 5-Chloro-2-Fluoro-4-hydroxybenzoate; 4-Hydroxy-5-chloro-2-fluorobenzoic Acid Ethyl Ester; Benzoic acid, 5-chloro-2-fluoro-4-hydroxy-, ethyl ester; 5-Chloro-2-fluoro-4-hydroxybenzoic acid ethyl ester; Ethyl 5-chloro-2-fluoro-4-hydroxybenzoate; CAS 1936365-38-6
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chloro-2-Fluoro-4-Hydroxybenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.