Description

Methyl3-Bromo-2-Fluoro-6-Iodobenzoate is a high-purity, multi-halogenated benzoate ester building block designed for advanced organic synthesis. This compound is valued for its unique halogen substitution pattern, which provides distinct reactivity and selectivity in cross-coupling and functionalization reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting complex small molecules.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where the halogen atoms serve as handles for further structural elaboration.
• Material Science Research: Serves as a precursor for synthesizing specialized organic ligands and monomers for advanced polymeric materials.
• Cross-Coupling Reactions: The iodine and bromine substituents make it an excellent substrate for Suzuki, Stille, and Negishi coupling reactions to form biaryl structures.
• Fluorine Chemistry Studies: The presence of a fluorine atom allows for research into the effects of fluorination on molecular properties like bioavailability and metabolic stability.
• Chemical Library Development: Employed in high-throughput and combinatorial chemistry to generate diverse compound libraries for screening.

Basic Information

Product Name	Methyl3-Bromo-2-Fluoro-6-Iodobenzoate
CAS No.	1936253-89-2
Molecular Formula	C8H5BrFIO2
Molecular Weight	358.93 g/mol
Synonyms	Methyl 3-Bromo-2-fluoro-6-iodobenzoate; Benzoic acid, 3-bromo-2-fluoro-6-iodo-, methyl ester; 3-Bromo-2-fluoro-6-iodobenzoic acid methyl ester; Methyl 3-bromo-2-fluoro-6-iodobenzoate; Methyl ester of 3-bromo-2-fluoro-6-iodobenzoic acid
EINECS	Contact for details

Quality Control

Every batch of Methyl3-Bromo-2-Fluoro-6-Iodobenzoate is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical research and development projects. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed data on purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.