Description

2-Chloro-5-Isopropoxy-3-Nitropyridine is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique molecular structure, featuring chloro, isopropoxy, and nitro substituents on the pyridine ring, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or photoactive compounds, due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and Industrial R&D: Utilized in exploratory chemistry for method development and creating libraries of novel heterocyclic compounds for screening.

Basic Information

Product Name	2-Chloro-5-Isopropoxy-3-Nitropyridine
CAS No.	1935294-81-7
Molecular Formula	C8H9ClN2O3
Molecular Weight	216.62 g/mol
Synonyms	3-Nitro-2-chloro-5-isopropoxypyridine; 2-Chloro-3-nitro-5-(propan-2-yloxy)pyridine; 5-Isopropoxy-2-chloro-3-nitropyridine; Pyridine, 2-chloro-5-(1-methylethoxy)-3-nitro-; 2-Chloro-5-(isopropyloxy)-3-nitropyridine; 2-Chloro-5-(propan-2-yloxy)-3-nitropyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Isopropoxy-3-Nitropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This compound should be handled in accordance with good laboratory and industrial hygiene practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.