Description

Ethyl 3-Bromocyclobutane-1-Carboxylate is a versatile brominated cyclobutane derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of a reactive bromine atom and an ester functional group on a strained cyclobutane ring, enabling complex molecular transformations. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those containing strained ring systems for enhanced biological activity.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the cyclobutane scaffold imparts unique properties.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Building block for synthesizing monomers and polymers with specific optical or mechanical properties derived from the cyclobutane core.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and cellular processes.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Negishi, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.

Basic Information

Product Name	Ethyl 3-Bromocyclobutane-1-Carboxylate
CAS No.	1934754-13-8
Molecular Formula	C7H11BrO2
Molecular Weight	207.07 g/mol
Synonyms	3-Bromocyclobutane-1-carboxylic acid ethyl ester; Ethyl 3-bromocyclobutanecarboxylate; 1-Carbethoxy-3-bromocyclobutane; 3-Bromo-1-ethoxycarbonylcyclobutane; Cyclobutanecarboxylic acid, 3-bromo-, ethyl ester; 1934754-13-8; Ethyl 3-bromocyclobutylcarboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Bromocyclobutane-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.