Description

5-Azaspiro[3.5]Nonan-8-One Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block with the CAS number 1909325-30-9. This spirocyclic compound is valued for its unique structural framework, which is critical for modulating the biological activity and physicochemical properties of novel drug candidates. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system (CNS) disorders, metabolic diseases, and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical space and improve drug-like properties.
• Process Chemistry Development: Serves as a critical starting material or intermediate in the scale-up and optimization of synthetic routes for candidate drugs.
• Academic Research: Employed in organic synthesis and methodology development for constructing complex spirocyclic and heterocyclic frameworks.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	5-Azaspiro[3.5]Nonan-8-One Hydrochloride
CAS No.	1909325-30-9
Molecular Formula	C8H14ClNO
Molecular Weight	175.66 g/mol
Synonyms	8-Oxo-5-azaspiro[3.5]nonane hydrochloride; 5-Azaspiro[3.5]nonan-8-one HCl; 5-Azaspiro[3.5]nonane-8-one hydrochloride; Spiro[3.5]nonan-8-one, 5-aza-, hydrochloride; 1909325-30-9
EINECS	Contact for details

Quality Control

Our 5-Azaspiro[3.5]Nonan-8-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.