Description

6-Oxa-1-Azaspiro[3.4]Octane Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is of significant value for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules with potential therapeutic applications. It is primarily sought after by R&D teams and process chemists in the pharmaceutical, biotechnology, and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disease research.
• Medicinal Chemistry: Used in scaffold hopping and lead optimization to explore new chemical space and improve drug-like properties.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker component due to its rigid, three-dimensional spirocyclic structure.
• Agrochemical Research: Intermediate in the development of new active ingredients with unique modes of action.
• Chemical Biology: Tool compound for probing biological systems and enzyme function.
• Academic Research: Used in universities and research institutes for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6-Oxa-1-Azaspiro[3.4]Octane Hydrochloride
CAS No.	1909319-43-2
Molecular Formula	C7H12ClNO
Molecular Weight	161.63 g/mol
Synonyms	1-Azaspiro[3.4]octan-6-one, oxime, hydrochloride; 6-Oxa-1-azaspiro[3.4]octane, hydrochloride; 6-Oxa-1-azaspiro[3.4]octane HCl; 1-Azaspiro[3.4]octan-6-one oxime hydrochloride; Spiro[oxetane-3,1'-pyrrolidine] hydrochloride, 2-oxa derivative; 6-Oxa-1-azaspiro[3.4]octane hydrocloride; 1909319-43-2
EINECS	Contact for details

Quality Control

Our 6-Oxa-1-Azaspiro[3.4]Octane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.