Description

2-Thia-7-Azaspiro[4.5]Decane 2,2-Dioxide Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure. This compound is of significant value in modern medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and metabolic disorder research pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing novel molecular libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• API Development: Used in the research and process development stages for new Active Pharmaceutical Ingredients, leveraging its spirocyclic core for metabolic stability.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the pharmaceutical industry.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-Thia-7-Azaspiro[4.5]Decane 2,2-Dioxide Hydrochloride
CAS No.	1909306-48-4
Molecular Formula	C8H16ClNO2S
Molecular Weight	225.74 g/mol
Synonyms	7-Aza-2-thiaspiro[4.5]decane 2,2-dioxide hydrochloride; 2-Thia-7-azaspiro[4.5]decane 2,2-dioxide HCl; 1-Azaspiro[4.5]decane-7-thiolane 2,2-dioxide hydrochloride; Spiro[piperidine-4,2'-thiolane] 1',1'-dioxide hydrochloride; 1909306-48-4; 2-Thia-7-azaspiro[4.5]decane, 2,2-dioxide, hydrochloride; 2,2-Dioxo-2-thia-7-azaspiro[4.5]decane hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 2-Thia-7-Azaspiro[4.5]Decane 2,2-Dioxide Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.