Description

5H-Pyrido[4,3-B]Indole-8-Carbonitrile is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block. This compound is valued for its unique fused-ring structure, which serves as a critical scaffold in medicinal chemistry for the development of novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical companies engaged in the synthesis of bioactive molecules, particularly for oncology and central nervous system (CNS) drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a privileged scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Oncology Drug Development: Serves as a core structure for developing potential kinase inhibitors and other anticancer agents.
• CNS-Active Compound Synthesis: Employed in the research and development of potential neuroprotective or neuromodulatory compounds.
• Agrochemical Research: May be utilized in the discovery of new active ingredients for crop protection.
• Material Science: Investigated as a building block for organic electronic materials due to its conjugated π-system.

Basic Information

Product Name	5H-Pyrido[4,3-B]Indole-8-Carbonitrile
CAS No.	1895766-22-9
Molecular Formula	C12H7N3
Molecular Weight	193.21 g/mol
Synonyms	8-Cyano-5H-pyrido[4,3-b]indole; 5H-Pyrido[4,3-b]indole-8-carbonitrile; Pyridoindole-8-carbonitrile; δ-Carboline-8-carbonitrile derivative; 8-CN-5H-Pyrido[4,3-b]indole; 1895766-22-9; 5H-β-Carboline-8-carbonitrile
EINECS	Contact for details

Quality Control

Our 5H-Pyrido[4,3-B]Indole-8-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.