Description

Methyl 3-(Aminomethyl)Imidazo[1,2-A]Pyridine-6-Carboxylate (Wx130143) is a high-purity, advanced pharmaceutical intermediate with the CAS number 1894881-03-8. This compound is a critical building block in modern medicinal chemistry, valued for its imidazopyridine core which is a privileged scaffold in drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly for central nervous system (CNS) and anti-infective applications.

Application

This specialized intermediate serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs). Its primary applications include:

• Pharmaceutical Research & Development: As a core scaffold for synthesizing novel drug candidates targeting various disease pathways.
• CNS Drug Synthesis: Used in the development of ligands for neurological receptors, applicable in treatments for anxiety, sleep disorders, and cognitive diseases.
• Anti-infective Agent Development: Serves as a building block for compounds with potential antibacterial or antiviral properties.
• Kinase Inhibitor Precursor: The imidazopyridine structure is integral to creating potent and selective kinase inhibitors for oncology research.
• Chemical Biology & Proteomics: Employed in the design of chemical probes to study enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of clinical trial materials.

Basic Information

Product Name	Methyl 3-(Aminomethyl)Imidazo[1,2-A]Pyridine-6-Carboxylate (Wx130143)
CAS No.	1894881-03-8
Molecular Formula	C10H11N3O2
Molecular Weight	205.21 g/mol
Synonyms	6-(Methoxycarbonyl)imidazo[1,2-a]pyridin-3-ylmethanamine; Methyl 3-(aminomethyl)imidazo[1,2-a]pyridine-6-carboxylate; WX-130143; Wx130143; 3-(Aminomethyl)-6-(methoxycarbonyl)imidazo[1,2-a]pyridine; Imidazo[1,2-a]pyridine-6-carboxylic acid, 3-(aminomethyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-(Aminomethyl)Imidazo[1,2-A]Pyridine-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for research and pre-clinical development. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.