Description

Homoserine, o-Methyl-, 1,1-Dimethylethyl Ester CAS NO 1894245-73-8 is a protected amino acid derivative, specifically a tert-butyl ester of O-methylhomoserine. This compound is a crucial high-purity building block in advanced organic synthesis, offering a stable and reactive handle for constructing complex molecules. It is primarily utilized by pharmaceutical research and fine chemical synthesis laboratories for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in peptide mimetics and protease inhibitors.
• Peptide Chemistry: Used for the incorporation of modified homoserine residues into synthetic peptides, enabling structure-activity relationship (SAR) studies.
• Chemical Biology Research: Serves as a precursor for designing molecular probes and enzyme substrates to study biological pathways.
• Agrochemical Synthesis: Intermediate in the development of advanced herbicides and plant growth regulators with specific modes of action.
• Ligand and Catalyst Development: Employed in the creation of chiral ligands and organocatalysts for asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high-purity, specialized amino acid derivatives.

Basic Information

Item	Details
Product Name	Homoserine, o-Methyl-, 1,1-Dimethylethyl Ester
CAS No.	1894245-73-8
Molecular Formula	C9H19NO3
Molecular Weight	189.25 g/mol
Synonyms	O-Methyl-L-homoserine tert-butyl ester; tert-Butyl O-methyl-L-homoserinate; (2S)-2-Amino-4-methoxybutanoic acid 1,1-dimethylethyl ester; L-Homoserine, O-methyl-, 1,1-dimethylethyl ester; (S)-2-Amino-4-methoxybutyric acid tert-butyl ester; tert-Butyl (S)-2-amino-4-methoxybutanoate; 1894245-73-8; Protected O-methylhomoserine
EINECS	Contact for details

Quality Control

Our Homoserine, o-Methyl-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation to ensure it meets the stringent requirements of research and cGMP-grade synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.