Description

tert-Butyl 3-Acetoxy-4-oxopiperidine-1-carboxylate is a high-purity, advanced pharmaceutical intermediate used in the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for constructing key piperidine-based scaffolds found in a variety of therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel drug candidates, particularly in the fields of neurology and oncology.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in the development of protease inhibitors for antiviral and anticancer therapies.
• Neurological Drug Development: Serves as a precursor for compounds targeting neurological disorders and central nervous system (CNS) diseases.
• Chemical Synthesis & Process R&D: Employed in route scouting, process optimization, and scale-up activities within medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs).
• Academic & Industrial Research: Used in academic laboratories and industrial R&D for exploring new chemical entities and biological activities.

Basic Information

Item	Details
Product Name	tert-Butyl 3-Acetoxy-4-oxopiperidine-1-carboxylate
CAS No.	1881288-56-7
Molecular Formula	C12H19NO5
Molecular Weight	257.28 g/mol
Synonyms	1-Boc-3-acetoxy-4-oxopiperidine; 1-(tert-Butoxycarbonyl)-3-acetoxy-4-piperidinone; 3-(Acetyloxy)-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-one; tert-Butyl 3-(acetyloxy)-4-oxo-1-piperidinecarboxylate; 3-Acetoxy-1-Boc-4-piperidinone; 4-Oxo-3-piperidinol acetate 1-Boc derivative; BOC-3-acetoxy-4-piperidinone; 1-N-Boc-3-acetoxy-4-piperidinone
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Acetoxy-4-oxopiperidine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.