Description

4-Chloro-2-Methyl-Benzoic Acid tert-Butyl Ester is a high-purity, synthetically valuable organic intermediate. This compound is crucial for its role as a protected carboxylic acid derivative, offering enhanced stability and reactivity control in complex multi-step synthesis. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the construction of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with substituted benzoic acid scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Serves as a versatile tert-butyl ester protecting group in multi-step synthetic routes, facilitating selective reactions.
• Material Science Research: Intermediate for developing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	4-Chloro-2-Methyl-Benzoic Acid tert-Butyl Ester
CAS No.	1872907-39-5
Molecular Formula	C12H15ClO2
Molecular Weight	226.70 g/mol
Synonyms	tert-Butyl 4-chloro-2-methylbenzoate; 4-Chloro-2-methylbenzoic acid tert-butyl ester; 2-Methyl-4-chlorobenzoic acid tert-butyl ester; Benzoic acid, 4-chloro-2-methyl-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 4-chloro-2-methylbenzoate; 4-Chloro-o-toluic acid tert-butyl ester; t-Butyl 4-chloro-2-methylbenzoate
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methyl-Benzoic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and batch-to-batch consistency for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.