Description

3-(1,3-Oxazol-5-Yl)Piperidine is a high-value, nitrogen-containing heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because its unique piperidine-oxazole hybrid structure provides a privileged scaffold for modulating biological activity and physicochemical properties in drug discovery. Pharmaceutical and agrochemical R&D teams need it as a critical intermediate for developing novel active ingredients, particularly in medicinal chemistry programs targeting central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new chemical entities (NCEs), especially for CNS-targeting drugs, kinase inhibitors, and GPCR modulators.
• Medicinal Chemistry Scaffold: Used as a core structural motif for constructing compound libraries via parallel synthesis and combinatorial chemistry for high-throughput screening (HTS).
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand Synthesis in Catalysis: Employed in the preparation of specialized ligands for transition metal catalysis, enabling novel asymmetric synthesis routes.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying enzyme function and protein-protein interactions within biological systems.
• Material Science Precursor: Acts as a monomer or functional additive in the synthesis of advanced polymers and functional materials.

Basic Information

Product Name	3-(1,3-Oxazol-5-Yl)Piperidine
CAS No.	1864062-33-8
Molecular Formula	C8H12N2O
Molecular Weight	152.20 g/mol
Synonyms	5-(Piperidin-3-yl)-1,3-oxazole; 3-(Oxazol-5-yl)piperidine; Piperidine, 3-(5-oxazolyl)-; 1,3-Oxazole, 5-(3-piperidinyl)-; 1864062-33-8; 3-(1,3-Oxazol-5-yl)piperidine; 5-(3-Piperidyl)oxazole
EINECS	Contact for details

Quality Control

Our 3-(1,3-Oxazol-5-Yl)Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.