Description

5-Chloro-3-(Piperidin-1-Ylsulfonyl)Pyridin-2-Amine is a high-purity, advanced pharmaceutical intermediate with a distinct sulfonamide-pyridine core structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel small-molecule drug candidates targeting a range of therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other enzyme-targeting molecules.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Serves as a core scaffold for developing tool compounds to study biological pathways and protein function.
• Custom Synthesis: Employed by fine chemical suppliers for the contract manufacturing of complex, non-commercial molecules for client R&D.
• Library Synthesis: A valuable reactant for generating diverse compound libraries for high-throughput screening (HTS) campaigns.
• Agrochemical Research: Potential intermediate in the development of new crop protection agents, leveraging its heterocyclic structure.

Basic Information

Product Name	5-Chloro-3-(Piperidin-1-Ylsulfonyl)Pyridin-2-Amine
CAS No.	1858250-67-5
Molecular Formula	C10H14ClN3O2S
Molecular Weight	275.76 g/mol
Synonyms	5-Chloro-3-(piperidin-1-ylsulfonyl)pyridin-2-amine; 2-Amino-5-chloro-3-(1-piperidinylsulfonyl)pyridine; 2-Pyridinamine, 5-chloro-3-(1-piperidinylsulfonyl)-; 5-Chloro-3-(piperidine-1-sulfonyl)pyridin-2-amine; 1858250-67-5; 5-Chloro-3-piperidin-1-ylsulfonyl-pyridin-2-ylamine
EINECS	Contact for details

Quality Control

Our 5-Chloro-3-(Piperidin-1-Ylsulfonyl)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.