Description

n-Pyridin-3-Yl-2-(Tetrahydro-2H-Pyran-4-Ylcarbonyl)Hydrazinecarbothioamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research targeting specific therapeutic areas. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of new drug candidates, particularly for central nervous system (CNS) or anti-infective therapies.
• Chemical Synthesis Building Block: Used in organic synthesis to construct complex molecular architectures containing pyridine and tetrahydropyran motifs.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead compound optimization within academic and industrial R&D laboratories.
• Agrochemical Development: Potential application as an intermediate in the synthesis of novel crop protection agents and pesticides.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	n-Pyridin-3-Yl-2-(Tetrahydro-2H-Pyran-4-Ylcarbonyl)Hydrazinecarbothioamide
CAS No.	1858249-71-4
Molecular Formula	C12H16N4O2S
Molecular Weight	280.35 g/mol
Synonyms	3-Pyridyl-2-(tetrahydropyran-4-carbonyl)hydrazinecarbothioamide; 2-(Oxane-4-carbonyl)-N-(pyridin-3-yl)hydrazine-1-carbothioamide; 1-(Pyridin-3-yl)-2-(tetrahydro-2H-pyran-4-carbonyl)hydrazinecarbothioamide; THP-Pyridine Hydrazinecarbothioamide Derivative; (Pyridin-3-yl)-N'-(tetrahydro-2H-pyran-4-oyl)hydrazinecarbothioamide
EINECS	Contact for details

Quality Control

Our n-Pyridin-3-Yl-2-(Tetrahydro-2H-Pyran-4-Ylcarbonyl)Hydrazinecarbothioamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.