Description

5-Bromo-2-(1H-Pyrrol-1-yl)-3-(trifluoromethyl)pyridine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is critical for research and development in the pharmaceutical and agrochemical sectors, where its unique halogenated and trifluoromethylated pyridine core enables the creation of novel bioactive molecules. It is primarily sought by medicinal chemists and process development scientists for constructing complex molecular architectures targeting a range of therapeutic and crop protection applications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the bromine and trifluoromethyl groups.
• Material Science: Acts as a functional monomer or cross-linking agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology: Employed as a molecular probe or tag in bioconjugation chemistry and proteomics research due to its reactive bromine site.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Item	Detail
Product Name	5-Bromo-2-(1H-Pyrrol-1-yl)-3-(trifluoromethyl)pyridine
CAS No.	1858241-88-9
Molecular Formula	C10H6BrF3N2
Molecular Weight	291.07 g/mol
Synonyms	5-Bromo-2-(1H-pyrrol-1-yl)-3-(trifluoromethyl)pyridine; 5-Bromo-2-(pyrrol-1-yl)-3-(trifluoromethyl)pyridine; 3-Trifluoromethyl-5-bromo-2-(1-pyrrolyl)pyridine; 1858241-88-9; 5-Bromo-2-(1H-pyrrol-1-yl)-3-trifluoromethylpyridine; 5-Bromo-2-(pyrrol-1-yl)-3-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-(1H-Pyrrol-1-yl)-3-(trifluoromethyl)pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles as determined by HPLC, NMR, and GC-MS. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring suitability for demanding research and pre-clinical development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.