Description

3-(3-Methoxy-4-Nitrophenyl)-9-Methyl-3,9-Diazaspiro[5.5]Undecane is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic diaza structure. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel therapeutic agents targeting central nervous system disorders. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new chemical entities (NCEs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially for neurological and psychiatric applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique spirocyclic scaffold.
• Preclinical Development: Serves as a critical raw material for producing batches of experimental compounds for pharmacological and toxicological evaluation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and novel bioactive molecules.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	3-(3-Methoxy-4-Nitrophenyl)-9-Methyl-3,9-Diazaspiro[5.5]Undecane
CAS No.	1854943-73-9
Molecular Formula	C20H29N3O3
Molecular Weight	359.47 g/mol
Synonyms	9-Methyl-3-(3-methoxy-4-nitrophenyl)-3,9-diazaspiro[5.5]undecane; 3,9-Diazaspiro[5.5]undecane, 3-(3-methoxy-4-nitrophenyl)-9-methyl-; 1854943-73-9; 3-(3-Methoxy-4-nitrophenyl)-9-methyl-3,9-diazaspiro[5.5]undecane; 9-Methyl-3-(3-methoxy-4-nitrophenyl)-3,9-diazaspiro[5.5]undecane; Spirocyclic diaza intermediate; Methoxy-nitrophenyl diazaspiro compound
EINECS	Contact for details

Quality Control

Our 3-(3-Methoxy-4-Nitrophenyl)-9-Methyl-3,9-Diazaspiro[5.5]Undecane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for demanding R&D and early-stage development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.