Description

Methyl (E)-3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl)acrylate is a high-purity, synthetic organic compound featuring both an acrylate ester and a pinacol boronate ester functional group, making it a versatile and valuable building block in advanced chemical synthesis. Its primary value lies in its dual reactivity, enabling its use in key cross-coupling reactions and polymer modifications. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl or styryl motifs.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents, herbicides, and fungicides, leveraging the boronate group for efficient carbon-carbon bond formation.
• Materials Science & Polymer Chemistry: Serves as a functional monomer or cross-linking agent for creating specialty polymers, liquid crystals, and organic electronic materials with tailored properties.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugation reagents, utilizing the acrylate moiety for Michael addition or polymerization-based tagging strategies.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for synthesizing electron-transport or emissive layer materials in OLED device fabrication.
• Academic & Industrial R&D: A critical reagent for methodological development in organic synthesis and for exploring new chemical spaces in discovery chemistry programs.

Basic Information

Item	Detail
Product Name	Methyl (E)-3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl)acrylate
CAS No.	1844870-85-4
Molecular Formula	C₁₆H₂₁BO₄
Molecular Weight	288.15 g/mol
Synonyms	(E)-Methyl 3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acrylate; Methyl (E)-3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propenoate; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)cinnamic acid methyl ester; Methyl trans-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acrylate; 1844870-85-4; Boronic acid, B-[4-[(1E)-3-methoxy-3-oxo-1-propen-1-yl]phenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our Methyl (E)-3-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl)acrylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, it is recommended to keep the material under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (E/Z Ratio by HPLC)	≥ 98:2 (E/Z)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.