Description

5-Methyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine-2-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a valuable pinacol boronate ester functional group. This compound is a critical building block in modern organic synthesis, enabling efficient cross-coupling reactions to construct complex molecular architectures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require complex heterocyclic structures.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and semiconductors.
• Chemical Synthesis: Enables the efficient introduction of a pyridine-boronic ester moiety into target molecules for further functionalization.
• Life Science Reagents: Employed in the creation of biochemical probes and labeled compounds for diagnostic and research applications.
• Catalyst Ligand Synthesis: Used as a precursor for synthesizing novel ligand systems in transition metal catalysis.

Basic Information

Item	Detail
Product Name	5-Methyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine-2-Carboxylic Acid Methyl Ester
CAS No.	1842396-18-2
Molecular Formula	C14H20BNO4
Molecular Weight	277.13 g/mol
Synonyms	Methyl 5-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinate; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-methylpyridine-2-carboxylic acid methyl ester; 5-Methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)picolinic acid methyl ester; Pinacol 5-Methyl-4-(methoxycarbonyl)pyridin-2-ylboronate; 1842396-18-2; Methyl 5-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinecarboxylate
EINECS	Contact for details

Quality Control

Our 5-Methyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyridine-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric oxygen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.