Description

(S)-6-Methyl-2-Oxa-5,8-Diazaspiro[3.5]Nonan-7-One is a high-value, chiral spirocyclic building block of significant interest in modern pharmaceutical research and development. Its unique structural framework, featuring a spiro center and multiple heteroatoms, makes it a critical intermediate for constructing complex molecules with potential biological activity. This compound is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disease targets.
• Medicinal Chemistry: Used in lead optimization and structure-activity relationship (SAR) studies to explore novel chemical space and improve drug-like properties.
• Process Chemistry: Serves as a starting material or advanced intermediate in the scalable synthesis of complex drug molecules under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology: Employed as a molecular scaffold for designing chemical probes and tool compounds to study biological pathways and protein function.
• Asymmetric Synthesis: Utilized as a chiral template or auxiliary in stereoselective synthesis to introduce specific three-dimensional configurations into target molecules.
• Library Synthesis: A valuable component for generating diverse compound libraries for high-throughput screening (HTS) in drug discovery campaigns.

Basic Information

Product Name	(S)-6-Methyl-2-Oxa-5,8-Diazaspiro[3.5]Nonan-7-One
CAS No.	1839060-89-7
Molecular Formula	C7H10N2O2
Molecular Weight	154.17 g/mol
Synonyms	(S)-6-Methyl-2-oxa-5,8-diazaspiro[3.5]nonan-7-one; (7S)-6-Methyl-2-oxa-5,8-diazaspiro[3.5]nonan-7-one; 1839060-89-7; (S)-Spirocyclic Oxadiazinone; (S)-6-Methyl-2-oxa-5,8-diazaspiro[3.5]nonane-7-one; (S)-Enantiomer of 6-Methyl-2-oxa-5,8-diazaspiro[3.5]nonan-7-one
EINECS	Contact for details

Quality Control

Our (S)-6-Methyl-2-Oxa-5,8-Diazaspiro[3.5]Nonan-7-One is manufactured under strict quality control protocols to ensure high chemical purity and chiral integrity, meeting the stringent requirements of pharmaceutical R&D. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) and standard impurity profiling. Certificates of Analysis (COA) with detailed specifications from advanced analytical techniques (HPLC, GC, NMR, MS) are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.