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Azido-Peg1-Methylamine CAS NO 1835759-88-0


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CAS No.:1835759-88-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Azido-Peg1-Methylamine is a heterobifunctional polyethylene glycol (PEG) linker featuring a reactive azide group and a primary amine. This compound is essential for creating stable, biocompatible conjugates in bioconjugation and materials science. It is primarily used by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic industries for applications such as antibody-drug conjugate (ADC) development, peptide modification, and surface functionalization.

Application

  • Bioconjugation and ADC Development: Serves as a versatile linker for connecting drugs, toxins, or fluorophores to antibodies, proteins, or peptides via click chemistry (with the azide) and amide bond formation (with the amine).
  • Peptide and Protein Modification: Used to introduce PEG chains (PEGylation) to improve solubility, stability, and pharmacokinetic properties of therapeutic biomolecules.
  • Surface Functionalization: Enables the covalent attachment of biomolecules to nanoparticles, microarrays, and other solid supports for biosensing and diagnostic applications.
  • Polymer and Materials Science: Acts as a building block for synthesizing functionalized hydrogels, smart polymers, and drug delivery systems.
  • Crosslinking Agent: Facilitates the creation of crosslinked networks in biomaterials and polymer matrices.
  • Fluorescent Probe Synthesis: Used to prepare labeled probes for imaging and cellular tracking studies.

Basic Information

Product Name Azido-Peg1-Methylamine
CAS No. 1835759-88-0
Molecular Formula C5H12N4O
Molecular Weight 144.18 g/mol
Synonyms 2-(2-Azidoethoxy)ethanamine; N-(2-Azidoethyl)-2-aminoethyl ether; Azido-PEG1-amine; Azido-EG1-amine; 2-(2-Azidoethoxy)ethylamine; Azidoethyl-O-ethylamine; PEG1-azide-amine; Amino-PEG1-azide
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Quality Control

Our Azido-Peg1-Methylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label/Certificate of Analysis. For long-term storage under inert atmosphere, consider storing under argon or nitrogen. Keep away from heat and incompatible materials.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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