Description

Acid-Peg4-T-Butyl Ester is a specialized bifunctional PEG derivative featuring a carboxylic acid group and a tert-butyl ester protecting group. This compound is engineered to serve as a versatile building block and linker in advanced organic synthesis and bioconjugation, offering controlled reactivity and solubility. It is particularly valuable for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require precise molecular assembly and functionalization.

Application

• Pharmaceutical Intermediates: Acts as a key linker in the synthesis of prodrugs, antibody-drug conjugates (ADCs), and targeted therapeutic agents.
• Bioconjugation & PEGylation: Used to modify peptides, proteins, and oligonucleotides to enhance solubility, stability, and pharmacokinetic properties.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent for creating hydrogels and smart polymeric materials with tailored degradation profiles.
• Surface Modification: Employed to functionalize nanoparticles, biosensors, and diagnostic devices to improve biocompatibility and introduce specific chemical handles.
• Chemical Biology Probes: Utilized in the development of activity-based probes and affinity labels for studying enzyme function and protein interactions.
• Material Science: Incorporated into coatings and composites to impart specific surface properties and controlled reactivity.

Basic Information

Product Name	Acid-Peg4-T-Butyl Ester
CAS No.	1835759-85-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	15-Aza-3,6,9,12-tetraoxapentadecanoic acid, 14-(1,1-dimethylethyl) ester; 2-[2-[2-[2-(2-tert-Butoxy-2-oxoethoxy)ethoxy]ethoxy]ethoxy]acetic acid; PEG4-acid-t-butyl ester; t-Butyl-PEG4-acid; Carboxy-PEG4-t-butyl ester; 4,7,10,13-Tetraoxahexadecanoic acid, 15-tert-butyl ester; Acid-PEG4-OtBu; tert-Butyl tetraethylene glycol acetate
EINECS	Contact for details

Quality Control

Our Acid-Peg4-T-Butyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.