Description

5-Chloro-2-(Propan-2-Yloxy)Pyridin-3-Ol is a high-purity pyridine derivative, a versatile chemical intermediate prized for its unique substitution pattern. Its core value lies in enabling the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where it serves as a critical building block for active ingredients. This compound is essential for R&D chemists and process development scientists in fine chemical manufacturing, offering a reliable route to novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers due to its electron-donating alkoxy group.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to diverse R&D projects.

Basic Information

Product Name	5-Chloro-2-(Propan-2-Yloxy)Pyridin-3-Ol
CAS No.	1826110-18-2
Molecular Formula	C8H10ClNO2
Molecular Weight	187.62 g/mol
Synonyms	3-Hydroxy-5-chloro-2-isopropoxypyridine; 5-Chloro-2-isopropoxy-3-pyridinol; 5-Chloro-3-hydroxy-2-isopropoxypyridine; 2-Isopropoxy-5-chloro-3-pyridinol; 5-Chloro-2-(1-methylethoxy)-3-pyridinol; 5-Chloro-2-(propan-2-yloxy)pyridin-3-ol; 1826110-18-2
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(Propan-2-Yloxy)Pyridin-3-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment, ensuring full traceability and compliance with your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.