Description

5-Chloro-2-Ethoxy-3-Iodopyridine is a high-purity, multi-functional halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a versatile intermediate for constructing complex molecules, offering significant value in pharmaceutical and agrochemical research and development. This compound is primarily targeted at R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in cross-coupling reactions (e.g., Suzuki, Stille) and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or organic light-emitting diode (OLED) components.
• Custom Synthesis and Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic and Industrial R&D: A valuable reagent for method development and exploring new chemical spaces in academic laboratories and corporate R&D centers.

Basic Information

Product Name	5-Chloro-2-Ethoxy-3-Iodopyridine
CAS No.	1826110-06-8
Molecular Formula	C7H7ClINO
Molecular Weight	283.49 g/mol
Synonyms	3-Iodo-5-chloro-2-ethoxypyridine; 2-Ethoxy-3-iodo-5-chloropyridine; 5-Chloro-3-iodo-2-ethoxypyridine; Pyridine, 5-chloro-2-ethoxy-3-iodo-; 1826110-06-8
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-2-Ethoxy-3-Iodopyridine is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Melting Point	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.