Description

5-Chloro-2-isopropoxy-3-iodopyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an indispensable intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists in the life sciences sector for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the preparation of novel herbicides, fungicides, and insecticides requiring specific halogenated pyridine cores.
• Material Science Precursor: Serves as a building block for functionalized ligands in catalysis and for creating specialty polymers.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the pharmaceutical and biotechnology industries.

Basic Information

Item	Details
Product Name	5-Chloro-2-isopropoxy-3-iodopyridine
CAS No.	1826109-98-1
Molecular Formula	C8H9ClINO
Molecular Weight	297.52 g/mol
Synonyms	3-Iodo-5-chloro-2-isopropoxypyridine; 5-Chloro-3-iodo-2-isopropoxypyridine; 2-Isopropoxy-5-chloro-3-iodopyridine; 5-Chloro-2-(1-methylethoxy)-3-iodopyridine; 5-Chloro-3-iodo-2-(propan-2-yloxy)pyridine; Pyridine, 5-chloro-2-(1-methylethoxy)-3-iodo-; (5-Chloro-3-iodopyridin-2-yl) isopropyl ether
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-2-isopropoxy-3-iodopyridine is produced under strict quality management protocols. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC purity, identity confirmation (IR, NMR), and impurity profiles. Our quality systems ensure traceability and consistency, supporting our clients' needs for regulatory filings and process validation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.