Description

(Z)-tert-Butyl (3-Methyl-4-Oxo-1,3,7-Triazaspiro[4.5]Decan-2-Ylidene)Carbamate is a sophisticated spirocyclic carbamate derivative, serving as a critical advanced pharmaceutical intermediate (API) in modern drug discovery. Its unique molecular architecture, featuring a fused triazaspiro ring system, makes it a valuable scaffold for constructing novel bioactive compounds. This high-purity intermediate is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Medicinal Chemistry Research: Used as a privileged scaffold in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its spirocyclic and heterocyclic features.
• Protease Inhibitor Development: Serves as a core structure in the design and synthesis of potential protease inhibitors, leveraging its carbamate and lactam functionalities.
• Chemical Biology Probes: Employed in the creation of specialized molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds under cGMP conditions.
• Academic Research: Used in university and institutional labs for pioneering research in organic synthesis methodology and new therapeutic modalities.

Basic Information

Product Name	(Z)-tert-Butyl (3-Methyl-4-Oxo-1,3,7-Triazaspiro[4.5]Decan-2-Ylidene)Carbamate
CAS No.	1824674-39-6
Molecular Formula	C14H24N4O3
Molecular Weight	296.37 g/mol
Synonyms	tert-Butyl (Z)-(3-methyl-4-oxo-1,3,7-triazaspiro[4.5]dec-2-ylidene)carbamate; 1,3,7-Triazaspiro[4.5]decane-2-carboxamide, N-(1,1-dimethylethoxy)-3-methyl-4-oxo-, (2Z)-; (2Z)-N-(tert-Butoxy)-3-methyl-4-oxo-1,3,7-triazaspiro[4.5]decane-2-carboxamide; BOC-Protected Spirocyclic Triaza Lactam; CAS 1824674-39-6; Spiro[4.5]decane Triaza Intermediate
EINECS	Contact for details

Quality Control

Our production of (Z)-tert-Butyl (3-Methyl-4-Oxo-1,3,7-Triazaspiro[4.5]Decan-2-Ylidene)Carbamate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS. We provide full traceability and detailed Certificates of Analysis (COA) upon request, ensuring compliance with the exacting standards required for pharmaceutical R&D and cGMP synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.