Description

tert-Butyl n-(2-Methyl-5-Oxo-Pyrrolidin-3-Yl)Carbamate is a high-purity, protected amino acid derivative and a key chiral building block in advanced organic synthesis. This compound is essential for the development of novel pharmaceutical intermediates and bioactive molecules, offering precise stereochemical control. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the synthesis of complex, high-value target compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other small molecule therapeutics.
• Peptidomimetics Research: Serves as a protected proline or proline-like building block for constructing peptide analogs and peptidomimetics with enhanced metabolic stability.
• Agrochemical Synthesis: Used in the research and development of novel, chiral agrochemicals such as herbicides and fungicides.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Asymmetric Catalysis Ligand Precursor: Acts as a precursor for chiral ligands used in asymmetric hydrogenation and other catalytic transformations.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and contract research organizations (CROs/CMOs) specializing in complex organic molecules.

Basic Information

Product Name	tert-Butyl n-(2-Methyl-5-Oxo-Pyrrolidin-3-Yl)Carbamate
CAS No.	1824602-08-5
Molecular Formula	C11H20N2O3
Molecular Weight	228.29 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)amino]-2-methyl-5-pyrrolidinone; 2-Methyl-5-oxo-3-pyrrolidinecarboxylic acid tert-butyl ester; tert-Butyl (2-methyl-5-oxopyrrolidin-3-yl)carbamate; Boc-3-amino-2-methyl-5-oxopyrrolidine; (3R)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-methyl-5-oxo-1-pyrrolidinecarboxylic acid tert-butyl ester (enantiomer); (3S)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-methyl-5-oxo-1-pyrrolidinecarboxylic acid tert-butyl ester (enantiomer); 1824602-08-5
EINECS	Contact for details

Quality Control

Our tert-Butyl n-(2-Methyl-5-Oxo-Pyrrolidin-3-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided for every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee (specify enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.