Description

Carbamic Acid, n-(4-Ethynylcyclohexyl)-, 1,1-Dimethylethyl Ester is a specialized organic building block featuring a unique combination of a carbamate protecting group and an ethynyl moiety. This compound matters as a versatile intermediate for advanced organic synthesis, enabling the construction of complex molecules through click chemistry and other coupling reactions. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery of new active ingredients, as well as by fine chemical manufacturers producing high-value specialty compounds. The product is identified by CAS number 1824233-64-8.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly for targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides with specific modes of action.
• Click Chemistry Reagent: The terminal alkyne group enables efficient Huisgen cycloaddition (copper-catalyzed azide-alkyne cycloaddition) for bioconjugation and material science applications.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for developing specialty polymers with tailored properties.
• Ligand and Catalyst Development: Provides a scaffold for constructing novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic and Industrial Research: A valuable tool for synthetic organic chemists exploring new reaction methodologies and molecular architectures.

Basic Information

Product Name	Carbamic Acid, n-(4-Ethynylcyclohexyl)-, 1,1-Dimethylethyl Ester
CAS No.	1824233-64-8
Molecular Formula	C₁₃H₂₁NO₂
Molecular Weight	223.31 g/mol
Synonyms	tert-Butyl N-(4-ethynylcyclohexyl)carbamate; N-(4-Ethynylcyclohexyl)carbamic Acid tert-Butyl Ester; BOC-4-Ethynylcyclohexylamine; 4-Ethynylcyclohexylamine BOC derivative; (4-Ethynylcyclohexyl)carbamic Acid 1,1-Dimethylethyl Ester; tert-Butyl (4-ethynylcyclohexyl)carbamate; N-Boc-4-ethynylcyclohexylamine
EINECS	Contact for details

Quality Control

Our production of Carbamic Acid, n-(4-Ethynylcyclohexyl)-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.